Heritability of specific language impairment depends on diagnostic criteria
نویسندگان
چکیده
منابع مشابه
Heritability of specific language impairment depends on diagnostic criteria
Heritability estimates for specific language impairment (SLI) have been inconsistent. Four twin studies reported heritability of 0.5 or more, but a recent report from the Twins Early Development Study found negligible genetic influence in 4-year-olds. We considered whether the method of ascertainment influenced results and found substantially higher heritability if SLI was defined in terms of r...
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background: identification of children with specific language impairment (sli) has been viewed as both necessity and challenge. investigators and clinicians use different tests and measures for this purpose. some of these tests/measures have good psychometric properties, but it is not sufficient for diagnostic purposes. a diagnostic procedure can be used for identification a specific population...
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Specific language impairment (SLI) is a multifactorial neurodevelopmental disorder which occurs unexpectedly and without an obvious cause. Over a decade of research suggests that SLI is highly heritable. Several genes and loci have already been implicated in SLI through linkage and targeted association methods. Recently, genome-wide association studies (GWAS) of SLI and language traits in the g...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2008
ISSN: 1601-1848,1601-183X
DOI: 10.1111/j.1601-183x.2007.00360.x